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Losartan should not be taken by people who are diabetic and taking aliskiren. [3] Anemia may occur, due to inhibition of the renin–angiotensin system. [17] As with other angiotensin receptor blockers, losartan may injure the liver, although this effect appears to be rare. [18]
Losartan/hydrochlorothiazide, sold under the brand name Hyzaar among others, is a fixed-dose combination medication used to treat high blood pressure when losartan is not sufficient. [1] [2] It consists of losartan, an angiotensin II receptor blocker; and hydrochlorothiazide, a thiazide diuretic. [1] [2] It is taken by mouth. [1] [2]
Losartan, the first ARB. Angiotensin II receptor blockers (ARBs), formally angiotensin II receptor type 1 (AT 1) antagonists, [1] also known as angiotensin receptor blockers, [2] [3] angiotensin II receptor antagonists, or AT 1 receptor antagonists, are a group of pharmaceuticals that bind to and inhibit the angiotensin II receptor type 1 (AT 1) and thereby block the arteriolar contraction and ...
Losartan, valsartan, candesartan, irbesartan, telmisartan and olmesartan all contain a biphenyl-methyl group. Losartan is partly metabolized to its 5- carboxylic acid metabolite EXP 3174, which is a more potent AT 1 receptor antagonist than its parent compound [ 17 ] and has been a model for the continuing development of several other ARBs.
ACV may interact with medications affecting potassium or insulin, such as diuretics like furosemide, insulin, and certain blood pressure medications like lisinopril and losartan, says Routhenstein ...
Commonly prescribed drugs are prescribed according to guidelines around the world. For instance, for ischemic heart disease, the American College of Cardiology/American Heart Association (ACC/AHA) guideline is used in the United States and the European Society of Cardiology (ESC) guideline is used in Europe.
A clinical trial done on over 7000 participants showed higher rates of nasopharyngitis in those taking valsartan/hydrochlorothiazide (2.4% versus 1.9% in placebo). [2] [12] A dose-related side effect seen is hypotension, occurring in 0.7% of participants on the highest dose of the medication.
It is taken by mouth. [2] Versions are available as the combinations benazepril/hydrochlorothiazide and benazepril/amlodipine. [2] Common side effects include feeling tired, dizziness, cough, and light-headedness with standing. [2] Serious side effects may include kidney problems, low blood pressure, high blood potassium, and angioedema. [2]