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Hyperandrogenism, especially high levels of testosterone, can cause serious adverse effects if left untreated. High testosterone levels are associated with other health conditions such as obesity, hypertension, amenorrhea (cessation of menstrual cycles), and ovulatory dysfunction, which can lead to infertility.
Testosterone, via its active metabolite 3α-androstanediol, is a potent positive allosteric modulator of the GABA A receptor. [150] Testosterone has been found to act as an antagonist of the TrkA and p75 NTR, receptors for the neurotrophin nerve growth factor (NGF), with high affinity (around 5 nM).
[49] [28] High dosages of testosterone (with levels of > 50 ng/dL) have a risk of masculinization (e.g., acne, hair growth, voice changes) with long-term therapy in women. [49] [28] High dosages of testosterone but not low dosages of testosterone enhance the effects of low dosages of estrogens on sexual desire.
A new study found that older men with higher levels of circulating testosterone were at an increased risk for atrial fibrillation. High testosterone levels linked to increased risk of AFib in ...
In healthy older men, abnormal testosterone levels were associated with a greater risk of developing AFib, according to a new study. In healthy older men, abnormal testosterone levels were ...
To support testosterone levels via diet, be mindful of foods that are high in polyunsaturated fatty acids, or PUFAs, such as vegetable oils (e.g. corn, soybean, peanut, and canola oils).
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