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  2. Seltorexant - Wikipedia

    en.wikipedia.org/wiki/Seltorexant

    Seltorexant, also known by its developmental code names MIN-202 and JNJ-42847922, is an orexin antagonist medication which is under development for the treatment of depression and insomnia. [3] [2] It is a selective antagonist of the orexin OX 2 receptor (2-SORA). [2] [4] [1] The medication is taken by mouth. [1]

  3. Lemborexant - Wikipedia

    en.wikipedia.org/wiki/Lemborexant

    Lemborexant is used in the treatment of insomnia in adults. [3]A major systematic review and network meta-analysis of medications for the treatment of insomnia published in 2022 found that lemborexant had an effect size (standardized mean difference (SMD)) against placebo for treatment of insomnia at 4 weeks of 0.36 (95% CI Tooltip confidence interval 0.08 to 0.63) and at 3 months of 0.41 (95% ...

  4. Why the FDA Rejected This New Insomnia Drug - AOL

    www.aol.com/news/2013-07-01-why-the-fda-rejected...

    Shares of Merck closed flat as the market digests the FDA rejection of new insomnia drug suvorexant. However, this rejection is not out of the blue despite a positive FDA advisory committee vote ...

  5. List of investigational sleep drugs - Wikipedia

    en.wikipedia.org/wiki/List_of_investigational...

    This is a list of investigational sleep drugs, or drugs for the treatment of sleep disorders that are currently under development for clinical use but are not yet approved. Chemical/generic names are listed first, with developmental code names, synonyms, and brand names in parentheses.

  6. Temazepam - Wikipedia

    en.wikipedia.org/wiki/Temazepam

    The paper cites a systematic review of the medical literature concerning insomnia medications and states almost all trials of sleep disorders and drugs are sponsored by the pharmaceutical industry, while this is not the case in general medicine or psychiatry. It cites another study that "found that the odds ratio for finding results favorable ...

  7. Drugs You Don't Need For Disorders You Don't Have - The ...

    highline.huffingtonpost.com/articles/en/sleep...

    Under pressure from lobbyists and Capitol Hill, the FDA in 1997 produced new guidelines declaring that companies’ ads just had to devote roughly equal time to the risks and benefits of a drug. One year later, spending on television drug ads had more than doubled, from $310 million to $664 million.

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