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Mesenchymal stem cells (MSCs), ... which is a rich source of hematopoietic stem cells. The umbilical cord is available after a birth. It is normally discarded, and ...
The umbilical cord lining membrane is a rich source of two strains of stem cells (CLSCs): epithelial stem cells (from the amniotic layer) (CLECs) and mesenchymal stem cells (from the sub-amniotic layer) (CLMCs). Discovered by Singapore-based CellResearch Corporation in 2004, this is the best known source for harvesting human stem cells.
The umbilical cord lining is a good source of mesenchymal and epithelial stem cells. Umbilical cord mesenchymal stem cells (UC-MSC) have been used clinically to treat osteoarthritis, autoimmune diseases, and multiple other conditions. Their advantages include a better harvesting, and multiplication, and immunosuppressive properties that define ...
Cord blood is being used to get stem cells with which to test in people with type 1 diabetes mellitus. [42] The stem cells from umbilical cord blood are also being used in the treatment of a number of blood diseases including blood cancers. [43] Cord blood is also being studied as a substitute for normal blood transfusions in the developing world.
Cells in Wharton's jelly express several stem cell genes, including telomerase. They can be extracted, cultured, and induced to differentiate into mature cell types such as neurons . [ 3 ] Wharton's jelly is therefore a potential source of adult stem cells , often collected from cord blood .
The FDA has approved five hematopoietic stem-cell products derived from umbilical cord blood, for the treatment of blood and immunological diseases. [11] In 2014, the European Medicines Agency recommended approval of limbal stem cells for people with severe limbal stem cell deficiency due to burns in the eye. [12]
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