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David Healy has argued that warning signs were available for many years prior to regulatory authorities moving to put warnings on antidepressant labels that they might cause suicidal thoughts. [213] At the time these warnings were added, others argued that the evidence for harm remained unpersuasive [ 214 ] [ 215 ] and others continued to do so ...
Use in pregnancy appears safe, but has not been well studied; use in breastfeeding is of unclear safety. [4] It is believed to work in part by anticholinergic and antihistamine mechanisms. [3] Meclizine was patented in 1951 and came into medical use in 1953. [5] It is available as a generic medication and often over the counter.
Desvenlafaxine is a synthetic form of the isolated major active metabolite of venlafaxine, and is categorized as a serotonin-norepinephrine reuptake inhibitor (SNRI). When most normal metabolizers take venlafaxine, approximately 70% of the dose is metabolized into desvenlafaxine, so the effects of the two drugs are expected to be very similar. [18]
The FDA has recalled thousands of bottles of the antidepressant duloxetine, sold under brand name Cymbalta, due to the presence of a possibly cancer-causing chemical.
The FDA recalled thousands of bottles of antidepressants after finding high levels of potentially cancer-causing chemicals. Here's what to look for.
The Food and Drug Administration (FDA) issued a Class II recall of more than 7,100 bottles of the antidepressant duloxetine due to the possible presence of a carcinogen. Duloxetine belongs to a ...
Most antidepressants, including SNRIs, are safe and effective in the geriatric population. The geriatric population is at greater risk for adverse effects relating to drug interaction as they are more likely to experience polypharmacy. [99] Decisions are often based on co-morbid conditions, drug interactions, and patient tolerance.
The Food and Drug Administration announced a Class II recall for more than 7,000 bottles of an antidepressant due to a chemical.. The recall was initiated earlier this month on Oct. 10. Duloxetine ...