Search results
Results From The WOW.Com Content Network
An enteric coating is a polymer barrier applied to oral medication that prevents its dissolution or disintegration in the gastric environment. [1] This helps by either protecting drugs from the acidity of the stomach, the stomach from the detrimental effects of the drug, or to release the drug after the stomach (usually in the upper tract of the intestine). [2]
Methods of administration include oral, sublingual (dissolving the drug under the tongue), and rectal. Parenteral administration is via a peripheral or central vein. [1] In pharmacology, the route of drug administration is important because it affects drug metabolism, drug clearance, and thus dosage. The term is from Greek enteros 'intestine'.
Enteric coated tablets are designed to dissolve in the intestine, not the stomach, because the drug present in the tablet causes irritation in the stomach. Administering medication rectally. The rectal route is an effective route of administration for many medications, especially those used at the end of life.
Anti-ulcer agents are medications or supplements used to cure the damage of mucosal layer on organs to prevent the damage from further extending to deeper regions to cause complications. An anti-ulcer medication for treating mouth ulcer is triamcinolone, a corticosteroid. Other anti-ulcer supplements include vitamin B2 and vitamin B12.
[16] [17] NICE recommends care home providers have a care home medicines policy that includes guidance on covert administration of medications by care home staff. [18] Nursing guidelines in the New Zealand state the overriding a patient's wishes to not receive medication if the healthcare worker perceives it to be in the patient's best interest.
For example, proton-pump inhibitors (PPIs) are enteric coated to protect them from decomposition under an acidic environment. [22] Co-administration of antacids with PPIs would lead to premature release into acidic gastric environments and inactivate PPIs before absorption.
Food substantially reduces didanosine bioavailability, and the drug should be administered on an empty stomach. [5] The half-life in plasma is only 1.5 hours, [5] but in the intracellular environment more than 12 hours. An enteric-coated formulation is now marketed as well.
Buccal tablets offer many advantages over other solid dosage forms also intended for oral administration (e.g. enteric-coated tablets, chewable tablets, and capsules). Buccal tablets can be considered in patients who experience difficulty in swallowing, since these tablets are absorbed into the blood stream between the gum and cheek.