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A motor neuron (or motoneuron or efferent neuron [1]) is a neuron whose cell body is located in the motor cortex, brainstem or the spinal cord, and whose axon (fiber) projects to the spinal cord or outside of the spinal cord to directly or indirectly control effector organs, mainly muscles and glands. [2]
Each area is made up of many segments. Motor and sensory nerve fibers to and from every area of the body are found in the spinal nerve. A dermatome is innervated by each segment of the spinal cord. The spinal cord is organized into segments, each corresponding to specific regions of the body: 8 cervical (neck) 12 thoracic (chest) 5 lumbar ...
The spinal cord functions primarily in the transmission of nerve signals from the motor cortex to the body, and from the afferent fibers of the sensory neurons to the sensory cortex. It is also a center for coordinating many reflexes and contains reflex arcs that can independently control reflexes. [ 1 ]
Many voluntary movements rely on spinal lower motor neurons, which innervate skeletal muscle fibers and act as a link between upper motor neurons and muscles. [2] [3] Cranial nerve lower motor neurons also control some voluntary movements of the eyes, face and tongue, and contribute to chewing, swallowing and vocalization. [4]
These neurons connect the brain to the appropriate level in the spinal cord, from which point nerve signals continue to the muscles by means of the lower motor neurons. The neurotransmitter glutamate transmits the nerve impulses from upper to lower motor neurons, where it is detected by glutamate receptors.
Motor pools in the spinal cord are clustered in distinct columns of motor neurons extending over multiple spinal cord segments; although, there is significant overlap. Motor pools that control proximal muscles are generally located medial to the ventral horn , while those that control distal muscles are located laterally.
Lamina VIII: motor interneurons; Lamina IX: hypaxial (body wall muscles), lateral (in limb regions) and medial (back muscles) motor neurons, also phrenic and spinal accessory nuclei at cervical levels, and Onuf's nucleus in the sacral region
CPG circuits thought to be involved in the control of locomotion consist of motor neurons and spinal interneurons and are located in the lower thoracic and lumbar regions of the vertebrate spinal cord, [31] and in each neuromere of the invertebrate ventral nerve cord. [32]