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[12] [13] [14] One interpretation is that depression manifests due to an imbalance of neurotransmitters in the brain, resulting in feelings of worthlessness and despair. Magnetic resonance imaging shows that the brains of people diagnosed with depression may have a hippocampus up to 10% smaller than those who do not exhibit signs of depression.
This article needs to be updated. The reason given is: Many outdated sources and information (older than five years). Please help update this article to reflect recent events or newly available information. (July 2024) Medical condition Major depressive disorder Other names Clinical depression, major depression, unipolar depression, unipolar disorder, recurrent depression Sorrowing Old Man (At ...
Nearly 18% of US adults — more than 1 in 6 — said they are currently depressed or getting treatment for depression, according to a 2023 Gallup Poll. In 2015, when Gallup first started ...
People with MDD show a number of biases in emotional processing, such as a tendency to rate happy faces more negatively, and a tendency to allocate more attentional resources to sad expressions. [67] Depressed people also have impaired recognition of happy, angry, disgusted, fearful and surprised, but not sad faces. [68]
Depression is a mental state of low mood and aversion to activity. [3] It affects about 3.5% of the global population, or about 280 million people worldwide, as of 2020. [4] Depression affects a person's thoughts, behavior, feelings, and sense of well-being. [5]
The number of people with depression has reached new highs—and so has antidepressant use. ... And like esketamine, it works fast. In clinical trials, people felt the effects in about a week.