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Dysembryoplastic neuroepithelial tumour (DNT, DNET) is a type of brain tumor.Most commonly found in the temporal lobe, DNTs have been classified as benign tumours. [1] These are glioneuronal tumours comprising both glial and neuron cells and often have ties to focal cortical dysplasia.
Focal means that it is limited to a focal zone in any lobe. [2] Focal cortical dysplasia is a common cause of intractable epilepsy in children and is a frequent cause of epilepsy in adults. There are three types of FCD with subtypes, including type 1a, 1b, 1c, 2a, 2b, 3a, 3b, 3c, and 3d, each with distinct histopathological features.
Focal cortical dysplasia is a brain malformation that may cause temporal lobe epilepsy. [27] This malformation may cause abnormal cortical layers ( dyslamination ), occur with abnormal neurons ( dysmorphic neurons, balloon cells ) and may occur with a brain tumor or vascular malformation. [ 27 ]
Brain mapping by the technique of cortical electrical stimulation or electrocorticography are other procedures used in the process of invasive testing for certain patients. [19] Once the epilepsy focus is located, the specific surgery involved in treatment is decided on. The type of surgery depends on the location of the seizure focal point.
Identification of common lesions associated with epilepsy like focal cortical dysplasia, mesial temporal sclerosis, microencephalocele, and heterotopia require thorough review of images by trained clinicians as the changes can be very subtle and easily missed if not specifically evaluated for.
Amygdalohippocampectomy is a surgical procedure for the treatment of epilepsy.It consists of the removal of the hippocampus, which has a role in memory, spatial awareness, and navigation, [1] and the amygdalae, which have a role in the processing and memory of emotional reactions, [2] both structures forming part of the limbic system of the brain.
Anatomical hemispherectomy refers to the resection and removal of an entire hemisphere of the brain, which includes all four lobes, with or without the removal of basal ganglia and thalamus. [ 6 ] Functional hemispherectomy refers to surgeries that disable the function of one hemisphere, while maintaining its blood supply and without physically ...
The idea of the cortical homunculus was created by Wilder Penfield. Cortical stimulation mapping is used for somatotopy to determine the areas of the cerebral cortex that connect through nerve fibers with different body parts. Cortical stimulation identifies which regions of the brain are vital for certain functions, thereby allowing a 'map' to ...