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Cholesterol is tested to determine for "normal" or "desirable" levels if a person has a total cholesterol of 5.2 mmol/L or less (200 mg/dL), an HDL value of more than 1 mmol/L (40 mg/dL, "the higher, the better"), an LDL value of less than 2.6 mmol/L (100 mg/dL), and a triglycerides level of less than 1.7 mmol/L (150 mg/dL).
where H is HDL cholesterol, L is LDL cholesterol, C is total cholesterol, T are triglycerides, and k is 0.20 if the quantities are measured in mg/dL and 0.45 if in mmol/L. There are limitations to this method, most notably that samples must be obtained after a 12 to 14 h fast and that LDL-C cannot be calculated if plasma triglyceride is >4.52 ...
Unit conversion formula from mmol/L to mg/dL [5] m g / d L = m m o l / L × m o l e c u l a r w e i g h t ÷ 10 {\displaystyle mg/dL=mmol/L\times molecular\ weight\div 10} Since the molecular mass of glucose C 6 H 12 O 6 is 180.156 g/mol, the factor between the two units is about 18, so 1 mmol/L of glucose is equivalent to 18 mg/dL.
However, there is another cluster containing many metabolic substances like cholesterol and glucose at the limit with the blue part (g/L or mmol/L). [ citation needed ] The unit conversions of substance concentrations from the molar to the mass concentration scale above are made as follows:
The Friedewald method is reasonably reliable for the majority of patients, but is notably inaccurate in patients with hypertriglyceridemia (> 400 mg/dL or 4.5 mmol/L). It also underestimates LDL-C in patients with low LDL-C (< 25 mg/dL or 0.6 mmol/L). It does not take into account intermediate-density lipoprotein. [1]
The osmol gap is typically calculated with the following formula (all values in mmol/L): = = ([+] + [] + []) In non-SI laboratory units: Calculated osmolality = 2 x [Na mmol/L] + [glucose mg/dL] / 18 + [BUN mg/dL] / 2.8 + [ethanol/3.7] [3] (note: the values 18 and 2.8 convert mg/dL into mmol/L; the molecular weight of ethanol is 46, but empiric data shows that it does not act as an ideal ...
Food intake prior to testing may cause elevated levels, up to 20%. Normal level is defined as less than 150 mg/dL. [46] Borderline high is defined as 150 to 199 mg/dL. [46] High level is between 200 and 499 mg/dL. [46] Greater than 500 mg/dL is defined as very high, [46] and is associated with pancreatitis and requires medical treatment. [47]
For people at high risk of cardiovascular disease, the recommended limit for total cholesterol is 4 mmol/L, and 2 mmol/L for LDL. [ 33 ] In the United States, the National Heart, Lung, and Blood Institute within the National Institutes of Health classifies total cholesterol of less than 200 mg/dL as "desirable", 200 to 239 mg/dL as "borderline ...