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Neomycin/polymyxin B/hydrocortisone, sold under the brand Otosporin among others, is a medication used to treat otitis externa (swimmer's ear) and certain eye disorders. [2] [3] It consists of the antibiotics neomycin and polymyxin B, and the steroid hydrocortisone. [3] It is used as an ear drop or eye drop. [2] [3]
It is also available as the combinations bacitracin/polymyxin B and neomycin/polymyxin B/bacitracin for use on the skin. [3] [4] Common side effects when given by injection include kidney problems, neurological problems, fever, itchiness, and rash. [1] Injections into muscle may result in significant pain. [1]
Neomycin affects the cochlea, which is found in the inner ear. [15] Hearing loss is caused by ear hair cell death, which occurs in response to treatment with neomycin. [15] Patients with existing tinnitus or sensorineural hearing loss are advised to speak with a healthcare practitioner about the risks and side effects prior to taking this ...
Neomycin/polymyxin B/bacitracin, also known as triple antibiotic ointment, is an antibiotic medication used to reduce the risk of infections following minor skin injuries. [ 1 ] [ 2 ] It contains the three antibiotics neomycin , polymyxin B , and bacitracin . [ 1 ]
The most important factor that must be taken into account when designing any type of drug delivery device, and specifically ocular devices, is the release rate of a drug. As discussed previously, the deliver rate and kinetics associated with drugs to the eye can reach levels that are toxic to the eye or could even cause undesirable side effects.
Eye drops or eyedrops are liquid drops applied directly to the surface of the eye usually in small amounts such as a single drop or a few drops. Eye drops usually contain saline to match the salinity of the eye. Drops containing only saline and sometimes a lubricant are often used as artificial tears to treat dry eyes or simple eye irritation ...