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In practice, this is inferred by the detection of only one of the mutually exclusive antibody light chains, kappa or lambda, on the entire population of the abnormal B cells. Normal B lymphocytes consist of a stew of different antibody-producing cells, resulting in a mixture of both kappa- and lambda-expressing cells.
The AST/ALT ratio or De Ritis ratio is the ratio between the concentrations of two enzymes, aspartate transaminase (AST) and alanine transaminase, aka alanine aminotransferase (ALT), in the blood of a human or animal. It is used as one of several liver function tests, and measured with a blood test.
Cicchetti (1994) [19] gives the following often quoted guidelines for interpretation for kappa or ICC inter-rater agreement measures: Less than 0.40—poor. Between 0.40 and 0.59—fair. Between 0.60 and 0.74—good. Between 0.75 and 1.00—excellent. A different guideline is given by Koo and Li (2016): [20] below 0.50: poor; between 0.50 and 0 ...