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  2. Addison's disease - Wikipedia

    en.wikipedia.org/wiki/Addison's_disease

    Addison's disease is named after Thomas Addison, the British physician who first described the condition in On the Constitutional and Local Effects of Disease of the Suprarenal Capsules (1855). [ 43 ] [ 44 ] He originally described it as "melasma suprarenale", but later physicians gave it the medical eponym "Addison's disease" in recognition of ...

  3. Spironolactone - Wikipedia

    en.wikipedia.org/wiki/Spironolactone

    A newer medication, eplerenone, has been approved by the US Food and Drug Administration (FDA) for the treatment of heart failure, and lacks the antiandrogenic effects of spironolactone. As such, it is far more suitable for men for whom long-term medication is being chosen.

  4. Adrenal insufficiency - Wikipedia

    en.wikipedia.org/wiki/Adrenal_insufficiency

    The most common cause of primary adrenal insufficiency (Addison's disease) overall is autoimmune adrenalitis. [2] The prevalence of Addison's disease ranges from 5 to 221 per million in different countries. [30] In children, congenital adrenal hyperplasia (CAH) is the most common cause of adrenal insufficiency, with an incidence 1 in 14,200 ...

  5. Syndrome of inappropriate antidiuretic hormone secretion

    en.wikipedia.org/wiki/Syndrome_of_inappropriate...

    However, demeclocycline has a 2–3 day delay in onset with extensive side effect profile, including skin photosensitivity, and nephrotoxicity. [19] Urea: oral daily ingestion has shown favorable long-term results with protective effects in myelinosis and brain damage. [19]

  6. Fludrocortisone - Wikipedia

    en.wikipedia.org/wiki/Fludrocortisone

    It is used primarily to replace the missing hormone aldosterone in various forms of adrenal insufficiency such as Addison's disease and the classic salt-wasting (21-hydroxylase deficiency) form of congenital adrenal hyperplasia. Due to its effects on increasing Na+ levels, and therefore blood volume, fludrocortisone is the first-line of ...

  7. Glucocorticoid - Wikipedia

    en.wikipedia.org/wiki/Glucocorticoid

    Glucocorticoid drugs currently being used act nonselectively, so in the long run they may impair many healthy anabolic processes. To prevent this, much research has been focused recently on the elaboration of selectively acting glucocorticoid drugs. Side effects include: Immunodeficiency (see section below)

  8. Adrenal gland disorder - Wikipedia

    en.wikipedia.org/wiki/Adrenal_gland_disorder

    Addison's disease, or primary adrenal insufficiency, is an uncommon chronic illness characterized by insufficient production of cortisol and aldosterone by the adrenal glands. [17] Chronic primary adrenal insufficiency is typically characterized by an extended period of malaise, fatigue, anorexia, weight loss, joint and back pain, and skin ...

  9. Dexamethasone - Wikipedia

    en.wikipedia.org/wiki/Dexamethasone

    Dexamethasone is a fluorinated glucocorticoid medication [10] used to treat rheumatic problems, a number of skin diseases, severe allergies, asthma, chronic obstructive pulmonary disease (COPD), croup, brain swelling, eye pain following eye surgery, superior vena cava syndrome (a complication of some forms of cancer), [11] and along with antibiotics in tuberculosis. [10]