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While Kybella, a form of deoxycholic acid, is the only FDA-approved injectable for fat reduction, other mesotherapy treatments remain unregulated and may carry risks.
Injection lipolysis is a controversial cosmetic procedure in which drug mixtures are injected into patients with the goal of destroying fat cells. This practice, using drugs generally based on phosphatidylcholine and deoxycholate (PCDC), evolved from the initial intravenous use of those drug formulations to treat blood disorders.
In the United States, deoxycholic acid, under the brand name Kybella, is approved by the Food and Drug Administration for reducing moderate-to-severe fat below the chin. [5] [6] When injected into submental fat, deoxycholic acid helps destroy adipocytes (fat cells), which are metabolized by the body over the course of several months. [6]
Deoxycholic acid is a naturally occurring bile acid that aids in the breakdown and absorption of dietary fat. When injected into subcutaneous fat, it causes the dissolution of the fat cell membranes, causing them to die. The destroyed fat cells are then gradually eliminated by the body's natural metabolic processes over the following weeks.
The Food and Drug Administration issued a warning about the dangers of using unauthorized versions of fat-dissolving injections, saying it has received reports of severe side effects, such as ...
The multi-billion dollar weight loss industry offers products ranging from diet pills and supplements to weight loss shakes and protein bars, all promising weight loss. However, these weight loss ...
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