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Adenovirus infection is a contagious viral disease, caused by adenoviruses, commonly resulting in a respiratory tract infection. [ 1 ] [ 9 ] Typical symptoms range from those of a common cold , such as nasal congestion , rhinitis , and cough , to difficulty breathing as in pneumonia . [ 9 ]
Adenovirus D26 structural model at atomic resolution [1]. Adenoviruses (members of the family Adenoviridae) are medium-sized (90–100 nm), nonenveloped (without an outer lipid bilayer) viruses with an icosahedral nucleocapsid containing a double-stranded DNA genome. [2]
Adenoviral keratoconjunctivitis, also known as epidemic keratoconjunctivitis, is a contagious eye infection, a type of adenovirus disease caused by adenoviruses. [1] It typically presents as a conjunctivitis with a sudden onset of a painful red eye, watery discharge and feeling that something is in the eye. [3]
Human adenovirus 41 (HAdV-F41), is an enteric Adenovirus, a nonenveloped virus with an icosahedral nucleocapsid containing a double-stranded DNA genome. [ 1 ] It can particularly target the gastrointestinal tract to cause gastroenteritis , with symptoms similar to rotavirus gastroenteritis and norovirus . [ 2 ]
Human adenovirus 36 (HAdV-36) or Ad-36 or Adv36 is one of 52 types of adenoviruses known to infect humans. AD-36, first isolated in 1978 from the feces of a girl suffering from diabetes and enteritis, [ 1 ] has long been recognized as a cause of respiratory and eye infections in humans. [ 2 ]
The example used for the following description is Human adenovirus E, a mastadenovirus with a 36 Kbp genome containing 38 protein-coding genes. [2] While the precise number and identity of genes varies among adenoviruses, the basic principles of genome organization and the functions of most of the genes described in this article are shared ...
The 2018 United States adenovirus outbreak was an occurrence in which an unusual number of adenovirus cases were reported at two locations, one in Maryland and one in New Jersey, from September to December 2018, resulting in deaths in both states. [1] [2] At least 35 people contracted the disease in each location of the outbreak.
Adenovirus early region 1A (E1A) is a gene expressed during adenovirus replication to produce a variety of E1A proteins. [1] It is expressed during the early phase of the viral life span. E1A encodes two major proteins in Ad5, translated after alternative splicing of the viral DNA transcript, that are able to cause a variety of different ...