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Normal urine contains only small amounts of urobilinogen, the end product of conjugated bilirubin after it has passed through the bile ducts and been metabolized in the intestine.
High levels of urobilinogen in urine may be a sign that: Your liver is making too much bilirubin because your body breaks down red blood cells faster than it can make them. This condition is called hemolytic anemia.
A low or negative result for urobilinogen on a urine test may indicate. A problem with the liver or the bile ducts, which can affect the body's ability to produce and excrete bilirubin; A problem with the production or breakdown of red blood cells; Urobilinogen level in urine could be low or absent due to
Although urobilinogen is normally found in the urine, higher or lower levels may be a sign of a liver problem. Read on to find out what urobilinogen is, how it can be tested, and what its levels may reveal about your health.
Urobilinogen is normally found in the urine in trace amounts (0.2 to 1.0 mg/dL). A urinalysis detects the levels of urobilinogen and is often recommended for people who have a high risk for liver damage or disease because of a family history of liver disease.
High levels of urobilinogen in your urine can indicate liver disease and some types of anemia. Low levels of urobilinogen in your urine may be a sign of liver, gallbladder, or bile duct disease. Urobilinogen is a type of pigment that the colon produces when it breaks down old red blood cells.
Bilirubinuria is the presence of bilirubin in the urine, usually detected while performing a routine urine dipstick test. Its presence is abnormal and can be the first clinical pointer of serious underlying hepatobiliary disorder even before clinical jaundice is appreciated.
The normal range for urobilinogen in urine is 0.1 to 1.0 mg/dL. Urinalysis, typically done with a dipstick test, measures these levels. Elevated urobilinogen (over 1.0 mg/dL) may signal liver disease or increased red blood cell breakdown, while low or absent levels could indicate a bile duct obstruction or liver dysfunction.
An increase in urine urobilinogen cannot occur in the context of cholestasis, as conjugated bilirubin is unable to pass into the gut and be reabsorbed. Causes of Increased Urine Urobilinogen. Haemolysis - immune, thrombotic microangiopathy, mechanical, inherited, infection, hypersplenism, drugs.
High levels of urobilinogen in the urine is a symptom of several health conditions, like liver disease and hemolytic anemia, which also cause increased bilirubin levels in the blood. Learn more about what causes this finding and how it is treated