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A Duke University animal study funded by the Sugar Association [25] found evidence that doses of Splenda (containing ~1% sucralose and ~99% maltodextrin by weight) between 100 and 1000 mg/kg BW/day, containing sucralose at 1.1 to 11 mg/kg BW/day, fed to rats reduced gut microbiota, increased the pH level in the intestines, contributed to ...
Sucrose intolerance or genetic sucrase-isomaltase deficiency (GSID) is the condition in which sucrase-isomaltase, an enzyme needed for proper metabolism of sucrose (sugar) and starch (e.g., grains), is not produced or the enzyme produced is either partially functional or non-functional in the small intestine.
During their premarket review for all of the high-intensity sweeteners approved as food additives, the FDA established an ADI defined as an amount in milligrams per kilogram of body weight per day (mg/kg bw/d), indicating that a high-intensity sweetener does not cause safety concerns if estimated daily intakes are lower than the ADI. [49]
Sucralose, a chemical found in Splenda, may have cancer-causing properties, a new study finds. Nutritionists offer alternatives to artificial sweeteners.
New research suggested that Splenda (which, yes, is hidden inside that bottle of Diet Pepsi) may cause serious health problems, including cancer, Eat Clean reports.
Overconsumption of sugar is correlated with excessive calorie intake and increased risk of weight gain and various diseases. [ 1 ] [ 4 ] [ 5 ] Individuals who consume 17%-21% of their daily calories from added sugar are reported to have a 38% higher risk of dying from cardiovascular disease compared to those who consume 8% of their daily ...