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  2. Inductive effect - Wikipedia

    en.wikipedia.org/wiki/Inductive_effect

    The strength of inductive effect is also dependent on the distance between the substituent group and the main group that react; the longer the distance, the weaker the effect. Inductive effects can be expressed quantitatively through the Hammett equation, which describes the relationship between reaction rates and equilibrium constants with ...

  3. Electrophilic aromatic directing groups - Wikipedia

    en.wikipedia.org/wiki/Electrophilic_aromatic...

    In general, the resonance effect of elements in the third period and beyond is relatively weak. This is mainly because of the relatively poor orbital overlap of the substituent's 3p (or higher) orbital with the 2p orbital of the carbon. Due to a stronger resonance effect and inductive effect than the heavier halogens, fluorine is anomalous.

  4. Phenethyl alcohol - Wikipedia

    en.wikipedia.org/wiki/Phenethyl_alcohol

    Phenethyl alcohol, or 2-phenylethanol, is an organic compound with the chemical formula C 6 H 5 CH 2 CH 2 OH. It is a colourless liquid with a pleasant floral odor. It occurs widely in nature, being found in a variety of essential oils. It is slightly soluble in water (2 ml per 100 ml of H 2 O), but miscible with most organic solvents.

  5. Electron-withdrawing group - Wikipedia

    en.wikipedia.org/wiki/Electron-withdrawing_group

    Electron-withdrawing groups exert an "inductive" or "electron-pulling" effect on covalent bonds. The strength of the electron-withdrawing group is inversely proportional to the pKa of the carboxylic acid. [2] The inductive effect is cumulative: trichloroacetic acid is 1000x stronger than chloroacetic acid.

  6. Phenyl group - Wikipedia

    en.wikipedia.org/wiki/Phenyl_group

    In organic chemistry, the phenyl group, or phenyl ring, is a cyclic group of atoms with the formula C6H5, and is often represented by the symbol Ph (archaically φ) or Ø. The phenyl group is closely related to benzene and can be viewed as a benzene ring, minus a hydrogen, which may be replaced by some other element or compound to serve as a ...

  7. Taft equation - Wikipedia

    en.wikipedia.org/wiki/Taft_equation

    where ⁡ is the ratio of the rate of the substituted reaction compared to the reference reaction, ρ* is the sensitivity factor for the reaction to polar effects, σ* is the polar substituent constant that describes the field and inductive effects of the substituent, δ is the sensitivity factor for the reaction to steric effects, and E s is ...

  8. Phenylethanol - Wikipedia

    en.wikipedia.org/wiki/Phenylethanol

    2-Phenylethanol (phenethyl alcohol) This page was last edited on 22 October 2023, at 17:24 (UTC). Text is available under the Creative Commons Attribution-ShareAlike ...

  9. Mesomeric effect - Wikipedia

    en.wikipedia.org/wiki/Mesomeric_effect

    The mesomeric effect as a result of p-orbital overlap (resonance) has absolutely no effect on this inductive effect, as the inductive effect has purely to do with the electronegativity of the atoms and their topology in the molecule (which atoms are connected to which). Specifically the inductive effect is the tendency for the substituents to ...