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The adults, who were the parents of three of the adolescents, all had symptoms during adolescence but were asymptomatic as adults. [5] Seeing as NTS is believed to have an autosomal dominant genetic pattern, the many differences observed regarding the symptoms of NTS can be explained as variable expressivity. Some of these differences include ...
Iron-deficiency anemia is mainly caused by blood loss, such as may occur during menses or gastrointestinal hemorrhage.This often results in a depapilled, atrophic glossitis, giving the tongue a bald and shiny appearance, along with pallor (paleness) of the lips and other mucous membranes a tendency towards recurrent oral ulceration, [6] and cheilosis (swelling of the lips). [7]
The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) [5] classifies the condition under "Other Specified Obsessive-Compulsive and Related Disorder" (300.3) as a body-focused repetitive behavior; the DSM-5 uses the more descriptive terms lip biting and cheek chewing (p. 263) instead of morsicatio buccarum.
Rarely, the nose, ears, nipples, or lips are affected. [1] The episodes classically result in the affected part turning white and then blue. [2] Often, numbness or pain occurs. [2] As blood flow returns, the area turns red and burns. [2] The episodes typically last minutes but can last several hours. [2]
Of patients that enrolled in a 1, 3, 6, 12 and 24 month study, perceived weakness was reported in 35.3%, 47.1% experienced numbness, 70.6% had tingling, cramps were present in 64.7% and after 24 months, only 5% had their symptoms resolved. Of all the patients, none developed Motor Neuron Disease. [11]
Syringomyelia symptoms include pain, weakness, numbness, and stiffness in the back, shoulders, arms or legs. Other symptoms include headaches, the inability to feel changes in the temperature, sweating, sexual dysfunction, and loss of bowel and bladder control.
[1] [2] Patients observe these symptoms and seek medical advice from healthcare professionals. Because most people are not diagnostically trained or knowledgeable, they typically describe their symptoms in layman's terms, rather than using specific medical terminology. This list is not exhaustive.
Chapped lips (also known as cheilitis simplex [5] or common cheilitis) [6] is characterized by the cracking, fissuring, and peeling of the skin of the lips, and is one of the most common types of cheilitis. [5] [7] While both lips may be affected, the lower lip is the most common site. [7]