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Two positive serology results, using different test methods, are required to confirm the diagnosis. [4] If the test results are inconclusive, additional testing methods such as Western blot can be used. [2] Various rapid diagnostic tests for Chagas disease are available.
Chagas disease can be prevented by avoiding insect bites through insecticide spraying, home improvement, bed nets, hygienic food, medical care, laboratory practices, and testing. [38] It can be diagnosed through a serological test, although the test is not very accurate. [18] Treatment is with medication, which may have severe side effects. [38]
Chagas disease is diagnosed using a physical exam and blood test. [18] The only treatment includes antiparasitics only from the CDC, which are not FDA approved. [ 19 ] Acute Chagas disease has a quick onset, the trypanosomes enter the bloodstream, they become amastigotes, and replicate.
Chagas is a potentially fatal neglected disease that affects between 8 and 13 million people worldwide. DNDi 's Time to Treat campaign is pushing for increased political interest in new treatments for Chagas disease, increased public awareness of the disease and treatment limitations and increased public and private investment in R&D.
Chagas disease is caused by Trypanosoma cruzi and is mostly spread by Triatominae. It is endemic to 21 countries in Latin America. There are over 30,000 new cases per year and 12,000 deaths due to the disease. [143] Eradication efforts focus on the elimination of vector-borne transmission and the elimination of the vectors themselves. [143]
The logo of the Drugs for Neglected Diseases initiative (DNDi) The Drugs for Neglected Diseases initiative (DNDi) is a collaborative, patients' needs-driven, non-profit drug research and development (R&D) organization that is developing new treatments for neglected diseases, notably leishmaniasis, sleeping sickness (human African trypanosomiasis, HAT), Chagas disease, [1] malaria, filarial ...
The most used method for epidemiological management and disease prevention resides within vector control, [26] mainly by the use of insecticides and taking preventative measures such as applying bug repellent on the skin, wearing protective clothing, and staying in higher quality hotels when traveling. Investing in quality housing would be ...
Trypanosoma brucei is a species of parasitic kinetoplastid belonging to the genus Trypanosoma that is present in sub-Saharan Africa.Unlike other protozoan parasites that normally infect blood and tissue cells, it is exclusively extracellular and inhabits the blood plasma and body fluids. [1]