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Micrograph of decidualized endometrium due to exogenous progesterone. H&E stain. The decidua has a histologically-distinct appearance, displaying large polygonal decidual cells in the stroma. These are enlarged endometrial stromal cells, which resemble epithelium (and are referred to as "epithelioid").
Decidualization is a process that results in significant changes to cells of the endometrium in preparation for, and during, pregnancy. This includes morphological and functional changes (the decidual reaction) to endometrial stromal cells (ESCs), the presence of decidual white blood cells (leukocytes), and vascular changes to maternal arteries.
Dr. Jessica Kingston, clinical professor ob-gyn at UC San Diego Health, tells Yahoo Life that a decidual cast is “a layer of tissue that is shed from the endometrium — lining of the uterus ...
What is a decidual cast? There are two main things to know about decidual casts right off the bat, Dr. Salena Zanotti, an OB-GYN at the Cleveland Clinic, tells TODAY.com. First, a decidual cast is ...
Decidual cells are also thought to control the invasion of the endometrium by trophoblast cells. [ 2 ] Experimentally, human endometrial stromal cells can be decidualized in culture by using analogs of cAMP and progesterone .
Ectopic decidua are decidual cells found outside inner lining of the uterus. This condition was first described in 1971 by Walker [1] and the name 'ectopic decidua' was coined by Tausig. [2] While ectopic decidua is most commonly seen during pregnancy, it rarely occurs in non-pregnant people, accompanied by bleeding and pain. [citation needed]
Signs and symptoms include spotting, bleeding, abdominal pain, and menstrual cramps. The resulting uterine tissue is called a decidual cast and must be passed through the cervix and vagina. [16] It typically takes the shape of the uterus itself. Membranous dysmenorrhea is extremely rare and there are very few reported cases.
The decidual cells originate from the stromal cells that are always present in the endometrium, and make up a new layer, the decidua. The rest of the endometrium, in addition, expresses differences between the luminal and the basal sides.
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