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People with type 2 diabetes taking metformin face lower risks of death from heart disease. The drug helps to treat gestational diabetes and polycystic ovarian syndrome, both of which cause high ...
There are a few groups of people who shouldn’t take metformin. Before taking metformin, let your doctor know if you have any medical conditions like kidney or liver problems or type 1 diabetes ...
Another small study on people without diabetes who were overweight or had obesity found that those taking metformin lost between 5.6 and 6.5 percent of their body weight. In contrast, the control ...
A 2017 review found that people with diabetes who were taking metformin had lower all-cause mortality. [231] They also had reduced cancer and cardiovascular disease compared with those on other therapies. [231] In people without diabetes, metformin does not appear to reduce the risk of cancer and cardiovascular disease. [237]
LDL can be grouped based on its size: large-low density LDL particles are described as pattern A, and small high-density ("small dense") LDL particles are pattern B. [14] Pattern B has been associated by some with a higher risk for coronary heart disease.
It decreases LDL by 15–30% and raises HDL by 3–5%, with little effect on triglycerides, but can cause a slight increase. Bile acid sequestrants may cause gastrointestinal problems and may also reduce the absorption of other drugs and vitamins from the gut. Ezetimibe is a selective inhibitor of dietary cholesterol absorption.