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  2. Enzyme induction and inhibition - Wikipedia

    en.wikipedia.org/wiki/Enzyme_induction_and...

    Enzyme induction is a process in which a molecule (e.g. a drug) induces (i.e. initiates or enhances) the expression of an enzyme. Enzyme inhibition can refer to the inhibition of the expression of the enzyme by another molecule; interference at the enzyme-level, basically with how the enzyme works.

  3. Enzyme inducer - Wikipedia

    en.wikipedia.org/wiki/Enzyme_inducer

    An enzyme inducer is a type of drug that increases the metabolic activity of an enzyme either by binding to the enzyme and activating it, or by increasing the expression of the gene coding for the enzyme. [1] [page needed] It is the opposite of an enzyme repressor.

  4. Regulation of gene expression - Wikipedia

    en.wikipedia.org/wiki/Regulation_of_gene_expression

    Enzyme induction is a process in which a molecule (e.g., a drug) induces (i.e., initiates or enhances) the expression of an enzyme. The induction of heat shock proteins in the fruit fly Drosophila melanogaster. The Lac operon is an interesting example of how gene expression can be regulated.

  5. Enzyme - Wikipedia

    en.wikipedia.org/wiki/Enzyme

    Induction or inhibition of these enzymes can cause drug interactions. [94] Enzyme levels can also be regulated by changing the rate of enzyme degradation. [1]: 30.1.1 The opposite of enzyme induction is enzyme repression.

  6. CYP3A4 - Wikipedia

    en.wikipedia.org/wiki/CYP3A4

    1576 n/a Ensembl ENSG00000160868 n/a UniProt P08684 n/a RefSeq (mRNA) NM_001202855 NM_001202856 NM_001202857 NM_017460 n/a RefSeq (protein) NP_001189784 NP_059488 n/a Location (UCSC) Chr 7: 99.76 – 99.78 Mb n/a PubMed search n/a Wikidata View/Edit Human Cytochrome P450 3A4 (abbreviated CYP3A4) (EC 1.14.13.97) is an important enzyme in the body, mainly found in the liver and in the intestine ...

  7. Induction - Wikipedia

    en.wikipedia.org/wiki/Induction

    Induction (play), an opening scene; Induction (teachers), support of novice teachers; Inductive reasoning aptitude; Collective Induction, in psychology; Hypnotic induction, causing hypnosis "Induction", a song by Broken Spindles from Fulfilled/complete "Induction" (short story), a short story by Greg Egan

  8. Inducer - Wikipedia

    en.wikipedia.org/wiki/Inducer

    The promoter is where RNA polymerase, the enzyme that copies the genetic sequence and synthesizes the mRNA, attaches to the DNA strand. Some genes are modulated by activators, which have the opposite effect on gene expression as repressors. Inducers can also bind to activator proteins, allowing them to bind to the operator DNA where they ...

  9. Drug interaction - Wikipedia

    en.wikipedia.org/wiki/Drug_interaction

    The majority of the enzymes are also involved in the metabolism of endogenous substances, such as steroids or sex hormones, which is also important should there be interference with these substances. The function of the enzymes can either be stimulated (enzyme induction) or inhibited (enzyme inhibition).