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In 1949, he performed the first successful treatment of a retinal detachment with a light beam (light coagulation) using a self-constructed device on the roof of the ophthalmic clinic at the University of Hamburg-Eppendorf. [13] [14] Results of using laser coagulation to treat diabetic retinopathy were first published in 1954.
Recovery of visual acuity usually follows. Treatment should be considered if resorption does not occur within 3–4 months, [19] spontaneously or as the result of counselling. [1] The available evidence suggests that half-dose (or half-fluence) photodynamic therapy is the treatment of choice for CSR with subretinal fluid for longer than 3–4 ...
Diabetic retinopathy (also known as diabetic eye disease) is a medical condition in which damage occurs to the retina due to diabetes.It is a leading cause of blindness in developed countries and one of the lead causes of sight loss in the world, even though there are many new therapies and improved treatments for helping people live with diabetes.
Photoimmunotherapy is an oncological treatment for various cancers that combines photodynamic therapy of tumor with immunotherapy treatment. Combining photodynamic therapy with immunotherapy enhances the immunostimulating response and has synergistic effects for metastatic cancer treatment. [38] [39] [40]
Dental infections tend to also respond better to photothermal therapy than photodynamic therapy, though both have a strong effect. [ 10 ] [ 11 ] [ 12 ] The efficacy of PDT for antimicrobial usage is limited by the properties of the membrane of the target cell such as the electrical gradient ( membrane potential ) and lipid composition.
Intraretinal microvascular abnormalities (IRMA) are abnormalities of the blood vessels that supply the retina of the eye, a sign of diabetic retinopathy. [1] IRMA can be difficult to distinguish from and is likely a precursor to retinal neovascularization. One way to distinguish IRMA from retinal neovascularization is to perform fluorescein ...
Light therapy, also called phototherapy or bright light therapy is the exposure to direct sunlight or artificial light at controlled wavelengths in order to treat a variety of medical disorders, including seasonal affective disorder (SAD), circadian rhythm sleep-wake disorders, cancers, neonatal jaundice, and skin wound infections.
The device was approved with data from a single-arm clinical trial that enrolled thirty people with severe retinitis pigmentosa; the longest follow-up on a trial subject was 38.3 months. [4] People in the trial received the implant in only one eye and tests were conducted with the device switched on, or switched off as a control. [ 5 ]