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Samuel Jones Gee in 1881. Samuel Jones Gee (13 September 1839 – 3 August 1911) was an English physician and paediatrician. [1] In 1888, Gee published the first complete modern description of the clinical picture of coeliac disease, and theorised on the importance of diet in its control.
EATL typically occurs in patients with a history of coeliac disease and who may have been previously diagnosed with Type I or II refractory disease, [9] but in any case, affected individuals present with worsening coeliac disease symptoms of abdominal pain, malabsorption, diarrhea, weight loss, fever or night sweats.
People who present with minor damage to the small intestine may have seronegative findings so many patients with coeliac disease often are missed. In patients with villous atrophy, anti-endomysial (EMA) antibodies of the immunoglobulin A (IgA) type can detect coeliac disease with a sensitivity and specificity of 90% and 99%, respectively. [90]
The charity renamed itself Coeliac UK in 2001 and has since established the All Party Parliamentary Group on coeliac disease and DH and worked with the Food Standards Agency to introduce a new law that governed the labelling of gluten-free food. [2] English actress Caroline Quentin is the current patron of the charity. [3]
The following is a list of notable people diagnosed with coeliac disease. Name Notability Reference Gordon Banks: British politician [1] Alyssa Baumann:
[41] [42] [33] As occurs in people with coeliac disease, the treatment is a gluten-free diet (GFD) strict and maintained, without making any dietary transgression. [37] Whereas coeliac disease requires adherence to a strict lifelong gluten-free diet, it is not yet known whether NCGS is a permanent, or a transient condition.
In medicine, the median arcuate ligament syndrome (MALS, also known as celiac artery compression syndrome, celiac axis syndrome, celiac trunk compression syndrome or Dunbar syndrome) is a rare [1] condition characterized by abdominal pain attributed to compression of the celiac artery and the celiac ganglia by the median arcuate ligament. [2]
As antibody-negative coeliac disease is recognised, HLA status, persistence or progression of the duodenal IEL numbers following a gluten challenge, followed by symptomatic improvement on a gluten-free diet, has been used to be more certain about the diagnosis, which was made in 22% of one series of over 200 adult cases.