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An opportunistic infection is a serious infection caused by pathogens (bacteria, fungi, parasites or viruses) ... Opportunistic Infection and HIV/AIDS
Additionally, people with AIDS often have systemic symptoms of infection like fevers, sweats (particularly at night), swollen glands, chills, weakness, and weight loss. [13] [14] The specific opportunistic infections that AIDS patients develop depend in part on the prevalence of these infections in the geographic area in which the patient lives.
Most of these conditions are opportunistic infections that are easily treated in healthy people. The staging system is different for adults and adolescents and children. [2] Stage I: HIV disease is asymptomatic and not categorized as AIDS. Stage II: include minor mucocutaneous manifestations and recurrent upper respiratory tract infections.
The primary causes of death from HIV/AIDS are opportunistic infections and cancer, both of which are frequently the result of the progressive failure of the immune system. [187] [210] Risk of cancer appears to increase once the CD4 count is below 500/μL. [33]
Over time, they cause acquired immunodeficiency syndrome (AIDS), [1] [2] a condition in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive. [3] Without treatment, the average survival time after infection with HIV is estimated to be 9 to 11 years, depending on the HIV subtype. [4]
Immune reconstitution inflammatory syndrome (IRIS) is a condition seen in some cases of HIV/AIDS or immunosuppression, in which the immune system begins to recover, but then responds to a previously acquired opportunistic infection with an overwhelming inflammatory response that paradoxically makes the symptoms of infection worse.
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