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Placental abruption occurs in about 1 in 200 pregnancies. [5] Along with placenta previa and uterine rupture it is one of the most common causes of vaginal bleeding in the later part of pregnancy. [6] Placental abruption is the reason for about 15% of infant deaths around the time of birth. [2] The condition was described at least as early as ...
Couvelaire uterus (also known as uteroplacental apoplexy) [1] is a rare but not a life-threatening condition in which loosening of the placenta (abruptio placentae) causes bleeding that penetrates into the uterine myometrium forcing its way into the peritoneal cavity. This condition makes the uterus very tense and rigid.
Risk factors such as diabetes, chronic blood pressure and multiple pregnancies can increase the risk of developing placental disease. [3] Also, exposure to sudden trauma can increase the risk of placental abruption which coincides with placental disease. [6] There is no target treatment available for placental disease.
Circumvallate placenta appears to be correlated with reduced placental efficacy due to increased placental thickness and abnormal villi function, affecting the Sflt/PlGF ratio. It is thought that obtaining Sflt/PlGF ratios can be used to determine deficiencies in placental function in cases of placental abnormalities. [3]
Placental abruption causes blood loss from the mother and loss of oxygen and nutrients to the placenta occasionally leading to preterm labour. [14] Other causes of placental abruption can be abdominal trauma or sudden decompression of amniotic fluid , however it is not uncommon for the cause of placental abruption to be unknown.
The first sign of umbilical cord prolapse is usually a sudden and severe decrease in fetal heart rate that does not immediately resolve. On fetal heart tracing (a linear recording of the fetal heart rate) this would usually look like moderate to severe variable decelerations. [6]
Pregnant woman has severe pregnancy-induced hypertension, [49] severe eclampsia [49] /preeclampsia, [41] active vaginal bleeding, [49] placental abruption, a cardiac disease, [49] or another condition which indicates that the pregnancy should not continue. [49] Maternal hemodynamic instability with bleeding [41]
Causes of increased foetal-maternal haemorrhage are seen as a result of trauma, placental abruption or may be spontaneous with no cause found. Up to 30ml of foetal-maternal transfusion may take place with no significant signs or symptoms seen in either mother or foetus. [3]