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  2. Cod liver oil - Wikipedia

    en.wikipedia.org/wiki/Cod_liver_oil

    Cod liver oil for human consumption is pale and straw-colored, with a mild flavor. Scandinavian Vikings produced cod liver oil by laying birch tree branches over a kettle of water, and fresh livers were laid over the branches. The water was brought to a boil and as the steam rose, the oil from the liver dripped into the water and was skimmed ...

  3. Hypervitaminosis A - Wikipedia

    en.wikipedia.org/wiki/Hypervitaminosis_A

    Cod liver oil, a potentially toxic source of vitamin A. Hypervitaminosis A can result from ingestion of too much vitamin A from diet, supplements, or prescription medications. Hypervitaminosis A results from excessive intake of preformed vitamin A. Genetic variations in tolerance to vitamin A intake may occur, so the toxic dose will not be the ...

  4. Discovery and development of direct Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    The p-methoxy group of apixaban connects to S1 pocket of FXa but does not appear to have any interaction with any residues in this region of FXa. The pyrazole N-2 nitrogen atom of apixaban interacts with Gln-192 and the carbonyl oxygen interacts with Gly-216. The phenyl lactam group of apixaban is positioned between Tyr-99 and Phe-174 and due ...

  5. Apixaban - Wikipedia

    en.wikipedia.org/wiki/Apixaban

    Apixaban is a highly selective, orally bioavailable, and reversible direct inhibitor of free and clot-bound factor Xa. Factor Xa catalyzes the conversion of prothrombin to thrombin, the final enzyme in the coagulation cascade that is responsible for fibrin clot formation. [ 27 ]

  6. Vitamin A - Wikipedia

    en.wikipedia.org/wiki/Vitamin_A

    Before the era of synthetic retinol, cod liver oil, high in vitamins A and D, was a commonly consumed dietary supplement. [77] [78] Invertebrates cannot synthesize carotenoids or retinol, and thus must accrue these essential nutrients from consumption of algae, plants or animals. [79] [80] [81]

  7. Fish-liver oil - Wikipedia

    en.wikipedia.org/wiki/Fish-liver_oil

    Fish-liver oil may refer to: Cod liver oil, an oil extracted from cod livers; Shark liver oil This page was last edited on 1 January 2016, at 07:37 (UTC). Text is ...