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Furosemide, sold under the brand name Lasix among others, is a loop diuretic medication used to treat edema due to heart failure, liver scarring, or kidney disease. [4] Furosemide may also be used for the treatment of high blood pressure . [ 4 ]
Topical nicotinamide and topical zinc are safe, however, there are no FDA pregnancy category ratings. [27] [28] Topical salicylic acid and topical dapsone are classified as FDA pregnancy category C. [23] [28] Acne medications to avoid during pregnancy include oral isotretinoin and topical tazarotene as there have been reports of birth defects.
[5] [4] It is unclear if it is safe in either pregnancy or breastfeeding. [5] It is only recommended in those who have a normal level of consciousness and stable blood pressure and heart rate. [4] It is classified as a volatile anaesthetic. [4] It was first made in 1948 by William T. Miller and came into medical use in the 1960s. [7]
Contraindicated in pregnancy: Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
It is unclear if use in pregnancy is safe for the baby. [1] It should not be used together with PDE5 Inhibitors. [1] Isosorbide dinitrate is in the nitrate family of medications and works by dilating blood vessels. [1] Isosorbide dinitrate was first written about in 1939. [3] It is on the World Health Organization's List of Essential Medicines. [4]
Bumetanide is a loop diuretic and works by decreasing the reabsorption of sodium by the kidneys. The main difference between bumetanide and furosemide is in their bioavailability and potency. About 60% of furosemide is absorbed in the intestine, and there are substantial inter- and intraindividual differences in bioavailability (range 10-90%).
Use during pregnancy is believed to result in harm to the baby. [5] It is in the angiotensin-converting-enzyme (ACE) inhibitor family of medications. [5] Enalapril was patented in 1978, and came into medical use in 1984. [7] It is on the World Health Organization's List of Essential Medicines. [8]
This lowers blood pressure and prevents excess fluid accumulation in heart failure. Metolazone is sometimes used together with loop diuretics such as furosemide or bumetanide, but these highly effective combinations can lead to dehydration and electrolyte abnormalities. It was patented in 1966 and approved for medical use in 1974. [1]