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[1] [2] Cleft lip and cleft palate can often be diagnosed during pregnancy with an ultrasound exam. [1] A cleft lip or palate can be successfully treated with surgery. [1] This is often done in the first few months of life for cleft lip and before eighteen months for cleft palate. [1] Speech therapy and dental care may also be needed. [1]
However, when growth of the mandibular process is impeded, a lip pit occurs. Lip pits begin to develop on day 36. Cleft lip begins to develop on day 40, and cleft palate emerges on day 50 of development. [3] There are three types of lip pits, which are classified according to their location: midline upper, comissural, and lower lip.
Holoprosencephaly-ectrodactyly-cleft lip/palate syndrome, also simply known as Hartsfield syndrome, is a rare genetic disorder characterized by the presence of variable holoprosencephaly, ectrodactyly, cleft lip and palate, alongside generalized ectodermal abnormalities.
Within craniofacial disorders and abnormalities, orofacial clefts, and specifically cleft lip (CL) and cleft palate (CP) are the most common in humans. [9] Occurrences of CL/P are most often (around seventy percent of cases) isolated and nonsyndromic, meaning they are not associated with a syndrome or inherited genetic conditions.
This is a list of cleft lip and palate organisations around the world. This is a dynamic list and may never be able to satisfy particular standards for completeness. You can help by adding missing items with reliable sources .
A cleft palate is one of the most common causes of VPI. Cleft palate is an anatomical abnormality that occurs in utero and is present at birth. This malformation can affect the lip and palate, or the palate only. A cleft palate can affect the mobility of the velopharyngeal valve, thereby resulting in VPI. [citation needed]
Smile Train is a nonprofit organization and charity providing corrective surgery for children with cleft lips and palates. [1] Headquartered in New York City and founded in 1999, Smile Train provides free corrective cleft surgery in 87 countries, [2] training local doctors and providing hospital funding for the procedures.
Cleft lip and palate is one of the most common occurring multi-factorial congenital disorder occurring in 1 in 500–1000 live births in several forms. [ 8 ] [ 9 ] [ 10 ] The most common form is combined cleft lip and palate and it accounts for approximately 50% of cases, whereas isolated cleft lip concerns 20% of the patients.