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Excessive doses of metoprolol can cause bradycardia, hypotension, metabolic acidosis, seizures, and cardiorespiratory arrest. Blood or plasma concentrations may be measured to confirm a diagnosis of overdose or poisoning in hospitalized patients or to assist in a medicolegal death investigation.
Alpha2 adrenergic agonists can also be used to treat anxiety and panic, such as generalized anxiety disorder, panic disorder, or PTSD. Alpha2-adrenergic receptor agonists, such as clonidine and guanfacine , act at noradrenergic autoreceptors to inhibit the firing of cells in the locus ceruleus, effectively reducing the release of brain ...
Furthermore, α-blockers can occasionally be used to treat anxiety and panic disorders, such as posttraumatic stress disorder (PTSD) induced nightmares. [6] Studies have also had great medical interest in testing alpha blockers, specifically α 2 blockers, to treat type II diabetes and psychiatric depression .
Anxiety disorders — characterized by uneasiness, worry, and fear — can cause various symptoms that affect how you think and behave. This can include changes in appetite (aka your body’s ...
It’s kind of a chicken and egg scenario: Anxiety may lead to high blood pressure. Untreated high blood pressure can set the stage for heart attack, stroke and other complications by damaging ...
Conversely, central nervous system-related benefits of beta blockers may include prevention and treatment of migraine, essential tremor, akathisia, anxiety, post-traumatic stress disorder, aggression, and obsessive–compulsive disorder. [76] Most beta blockers are lipophilic and can cross into the brain, but there are a number of exceptions. [76]