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Pyroglutamic acid (also known as PCA, 5-oxoproline, pidolic acid) is a ubiquitous but understudied natural amino acid derivative in which the free amino group of glutamic acid or glutamine cyclizes to form a lactam. [1] The names of pyroglutamic acid conjugate base, anion, salts, and esters are pyroglutamate, 5-oxoprolinate, or pidolate.
Principal component analysis (PCA) is a linear dimensionality reduction technique with applications in exploratory data analysis, visualization and data preprocessing.. The data is linearly transformed onto a new coordinate system such that the directions (principal components) capturing the largest variation in the data can be easily identified.
In statistics, principal component regression (PCR) is a regression analysis technique that is based on principal component analysis (PCA). PCR is a form of reduced rank regression. [1] More specifically, PCR is used for estimating the unknown regression coefficients in a standard linear regression model.
Sparse principal component analysis (SPCA or sparse PCA) is a technique used in statistical analysis and, in particular, in the analysis of multivariate data sets. It extends the classic method of principal component analysis (PCA) for the reduction of dimensionality of data by introducing sparsity structures to the input variables.
Output after kernel PCA, with a Gaussian kernel. Note in particular that the first principal component is enough to distinguish the three different groups, which is impossible using only linear PCA, because linear PCA operates only in the given (in this case two-dimensional) space, in which these concentric point clouds are not linearly separable.
The 2014 guaranteed algorithm for the robust PCA problem (with the input matrix being = +) is an alternating minimization type algorithm. [12] The computational complexity is () where the input is the superposition of a low-rank (of rank ) and a sparse matrix of dimension and is the desired accuracy of the recovered solution, i.e., ‖ ^ ‖ where is the true low-rank component and ^ is the ...
PCA may refer to: Medicine and biology. Patient-controlled analgesia; Plate count agar in microbiology; Polymerase cycling assembly, for large DNA oligonucleotides;
In animals, doses of PCA of 0.5 to 5 mg/kg acutely produce a variety of behavioral and neurochemical effects thought to be due to serotonin release. [3] [19] [20] Consequent enhancement of serotonergic signaling, serotonergic effects like myoclonus, the serotonin behavioral syndrome, including tremor, rigidity, Straub tail, hindlimb abduction, lateral head weaving, and reciprocal forepaw ...