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Dakin's solution is a dilute solution of sodium hypochlorite (0.4% to 0.5%) and other stabilizing ingredients, traditionally used as an antiseptic, e.g. to cleanse wounds in order to prevent infection. [1] The preparation was for a time called also Carrel–Dakin solution or Carrel–Dakin fluid. [2]
The use of antiseptics on open wounds is justified in terms of prevention/treatment of infection and improved healing outcomes. Criteria by which a wound cleansing agent could be deemed suitable for use on wounds include: non-toxic to mammalian cells; broad spectrum in action; reduction of wound bioburden; maintaining optimal moist wound ...
Saline (also known as saline solution) is a mixture of sodium chloride (salt) and water. [1] It has a number of uses in medicine including cleaning wounds, removal and storage of contact lenses, and help with dry eyes. [2] By injection into a vein, it is used to treat hypovolemia such as that from gastroenteritis and diabetic ketoacidosis.
Frequent use is not recommended in people with thyroid problems or who are taking lithium. [2] Povidone-iodine is a chemical complex of povidone, hydrogen iodide, and elemental iodine. [4] The recommended strength solution contains 10% Povidone, with total iodine species equaling 10,000 ppm or 1% total titratable iodine. [4]
It is used as a 1-3 % solution for cleaning roadside accident wounds. [3] ICI also introduced Savlon, which was a combination of cetrimide and chlorhexidine. ICI later sold the Savlon brand OTC to Johnson & Johnson in May 1992. [4]
The evidence supporting the most effective technique is not clear and there is insufficient evidence to conclude whether cleaning wounds is beneficial for promoting healing or whether wound cleaning solutions (polyhexamethylene biguanide, aqueous hydrogen peroxide, etc.) are better than sterile water or saline solutions to help venous leg ...