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Risk factors for developing multiple dermatofibromas include lupus, HIV, blood cancer and some medicines that weaken immunity. [3] It is usually diagnosed by its appearance, but a biopsy may be required. [3] Other bumps such as granular cell tumor, melanoma, clear cell acanthoma and dermatofibrosis lenticularis disseminata may look similar. [3]
The World Health Organization in 2020 classified the fibro sarcomatous DFSP (DFSP-FS) variant (also termed dermatofibrosarcoma protuberans, fibro sarcomatous) of the dermatofibrosarcoma protuberans as a specific form of the intermediate (rarely metastasizing) fibroblastic and myofibroblastic tumors and other variants of this disorder as a specific form of the intermediate (locally aggressive ...
List of cutaneous conditions associated with increased risk of nonmelanoma skin cancer; List of cutaneous conditions associated with internal malignancy; List of cutaneous conditions caused by mutations in keratins; List of cutaneous neoplasms associated with systemic syndromes; List of cutaneous conditions caused by problems with junctional ...
The PDGFB gene, which directs production of platelet-derived growth factor subunit B (PDGFβ) protein, is normally located in band 13.1 on the q arm of chromosome 22. The COL1A1 and PDGFB genes in DFSP-FS and DFSP are most commonly merged as result of the formation of a small supernumerary ring chromosome , i.e. an extra ring-shaped chromosome ...
Dermatofibroma (benign fibrous histiocytoma, dermal dendrocytoma, fibrous dermatofibroma, fibrous histiocytoma, fibroma simplex, histiocytoma, nodular subepidermal fibrosis, sclerosing hemangioma) Dermatofibrosarcoma protuberans
Behind the direct cause there are a number of genetic and environmental risk factors. [4] Patients who are diagnosed with PCT typically seek treatment following the development of photosensitivities causing blisters and erosions on exposed areas of the skin. This is usually observed in the face, hands, forearms, and lower legs.
Scleroderma in pregnancy is a complex situation; it increases the risk to both mother and child. [49] Overall, scleroderma is associated with reduced fetal weight for gestational age. [ 49 ] The treatment for scleroderma often includes known teratogens such as cyclophosphamide, methotrexate, mycophenolate , etc., so careful avoidance of such ...
Studies have shown existence of low-risk human papillomaviruses 6 and 11 in skin tags, hinting at a possible role in their pathogenesis, [3] although a 2012 study found no association between skin tags and either low- or high-risk HPV. [4] Acrochorda have been reported to have a prevalence of 46% in the general population. [5]