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  2. What is gabapentin? Here's why it's so controversial. - AOL

    www.aol.com/gabapentin-heres-why-controversial...

    Here's who gabapentin was originally approved for, what it's used for today and why it's becoming a drug of increasing concern for abuse and misuse. What's the latest health trend?!

  3. Gabapentin - Wikipedia

    en.wikipedia.org/wiki/Gabapentin

    After Kentucky implemented stricter legislation regarding opioid prescriptions in 2012, there was an increase in gabapentin-only and multi-drug use from 2012 to 2015. The majority of these cases were from overdose in suspected suicide attempts. These rates were also accompanied by increases in abuse and recreational use. [167]

  4. Drug withdrawal - Wikipedia

    en.wikipedia.org/wiki/Drug_withdrawal

    Drug withdrawal, drug withdrawal syndrome, or substance withdrawal syndrome [1] is the group of symptoms that occur upon the abrupt discontinuation or decrease in the intake of pharmaceutical or recreational drugs. In order for the symptoms of withdrawal to occur, one must have first developed a form of drug dependence.

  5. Kindling (sedative–hypnotic withdrawal) - Wikipedia

    en.wikipedia.org/wiki/Kindling_(sedative...

    Kindling due to substance withdrawal is the neurological condition which results from repeated withdrawal episodes from sedative–hypnotic drugs such as alcohol and benzodiazepines. Each withdrawal leads to more severe withdrawal symptoms than in previous episodes.

  6. Physical dependence - Wikipedia

    en.wikipedia.org/wiki/Physical_dependence

    addiction – a biopsychosocial disorder characterized by persistent use of drugs (including alcohol) despite substantial harm and adverse consequences addictive drug – psychoactive substances that with repeated use are associated with significantly higher rates of substance use disorders, due in large part to the drug's effect on brain ...

  7. Prescription drug addiction - Wikipedia

    en.wikipedia.org/wiki/Prescription_Drug_Addiction

    Prescription drug addiction is the chronic, repeated use of a prescription drug in ways other than prescribed for, including using someone else’s prescription. [3] [4] A prescription drug is a pharmaceutical drug that may not be dispensed without a legal medical prescription.

  8. NMDA receptor antagonist - Wikipedia

    en.wikipedia.org/wiki/NMDA_receptor_antagonist

    Has been used, albeit with limited evidence, to treat opioid and other addictions. [55] [56] Remacemide: principle metabolite is an uncompetitive antagonist with a low affinity for the binding site. [57] Rhynchophylline an alkaloid, found in Kratom and Rubiaceae. Gabapentin: a calcium α 2 δ ligand that is commonly used in diabetic neuropathy ...

  9. Opioid withdrawal - Wikipedia

    en.wikipedia.org/wiki/Opioid_withdrawal

    This allows the body to adapt to the absence of drugs to reduce the withdrawal symptoms. The most commonly used strategy is to offer opioid drug users long-acting opioid drugs and slowly taper the dose of the drug. Methadone, buprenorphine-­naloxone, and naltrexone are all commonly used medications for opioid use disorder. [19]