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Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) defines idiopathic hypersomnia as EDS without narcolepsy or the associated features of other sleep disorders. [9] It occurs in the absence of medical problems or sleep disruptions, such as sleep apnea , that can cause secondary hypersomnia.
A GABA reuptake inhibitor (GRI) is a type of drug which acts as a reuptake inhibitor for the neurotransmitter gamma-Aminobutyric acid (GABA) by blocking the action of the gamma-Aminobutyric acid transporters (GATs). This in turn leads to increased extracellular concentrations of GABA and therefore an increase in GABAergic neurotransmission. [1]
“Of importance, if sleep apnea affects the brain health and increases the risk for dementias, then treatment of it can serve as a strategy to improve brain health and prevent these disorders ...
"To diagnose sleep apnea on a home or in-lab sleep test, we count the number of disturbances in a patient's breathing and divide it by the amount of time they slept to come up with a per-hour ...
GABA is a very important neurotransmitter in animal brains, and a low concentration of GABA in mammalian brains has been linked to several neurological disorders, including Alzheimer's disease and Parkinson's disease. [9] [10] Because GABA-T degrades GABA, the inhibition of this enzyme has been the target of many medical studies. [9]
Sleep apnea is a common sleep disorder that affects more than 20 percent of people in the United States. ... impaired mental function or mood disorders. Because your sleep is so regularly ...
GABA is sold as a dietary supplement in many countries. It has been traditionally thought that exogenous GABA (i.e., taken as a supplement) does not cross the blood–brain barrier, but data obtained from more recent research (2010s) in rats describes the notion as being unclear. [2] [3] The carboxylate form of GABA is γ-aminobutyrate.
Sleep apnea, obstructive sleep apnea, obstruction of the airway during sleep, causing lack of sufficient deep sleep, often accompanied by snoring. Other forms of sleep apnea are less common. [ 89 ] Obstructive sleep apnea (OSA) is a medical disorder that is caused by repetitive collapse of the upper airway (back of the throat) during sleep.