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As a blood pressure medication, spironolactone is usually prescribed at a dose of 25 milligrams a day. For acne, the dosage is higher: it’s often started at 50 mg and then titrated up to 100 mg ...
Spironolactone may be more effective than birth control pills in the treatment of acne, and the combination of spironolactone with a birth control pill may have greater effectiveness for acne than either alone. [85] In addition, some clinical research has found that flutamide is more effective than spironolactone in the treatment of acne. [64]
Spironolactone: Spironolactone is used to treat high blood pressure but is also prescribed off-label for treating acne in women. Spironolactone reduces the amount of androgen hormones in your body ...
The best ways to treat and prevent hormonal acne. There are several different treatment options that can help you get rid of ... (There is also a new topical version of spironolactone called ...
The AR antagonism of spironolactone mostly underlies its antiandrogenic activity and is the major mechanism responsible for its therapeutic benefits in the treatment of androgen-dependent conditions like acne, hirsutism, and pattern hair loss and its usefulness in hormone therapy for transgender women.
The medication appears to be effective in the treatment of acne in males, with one study finding that a high dosage reduced inflammatory acne lesions by 73%. [ 130 ] [ 131 ] However, spironolactone and cyproterone acetate's side effects in males, such as gynecomastia , sexual dysfunction , and decreased bone mineral density , generally make ...