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Norgestimate, sold under the brand name Ortho Tri-Cyclen among others, is a progestin medication which is used in birth control pills for women and in menopausal hormone therapy. [1] [3] [4] [5] The medication is available in combination with an estrogen and is not available alone. [6] It is taken by mouth. [1]
In 1989, the FDA approved Ortho Cyclen containing the first new progestin (norgestimate) approved in over 20 years in the United States. In 1992, Ortho introduced Ortho Tri-Cyclen in the United States, which in 1996 became the first oral contraceptive with an FDA-approved non-contraceptive indication (treatment of moderate acne).
All contain an estrogen, ethinylestradiol or mestranol, [1] [2] in varying amounts, and one of a number of different progestogens. (Regarding the estrogen, the inactive 3-methyl ether of ethinylestradiol, which must be metabolized by the liver into the active ethinylestradiol; 50 μg of mestranol is equivalent to only 35 μg of ethinylestradiol and should not be used when high-dose [50 μg ...
This is a list of progestogens (progesterone and progestins) and formulations that are approved by the FDA Tooltip Food and Drug Administration in the United States. . Progestogens are used as hormonal contraceptives, in hormone replacement therapy for menopausal symptoms, and in the treatment of gynecological
These include Ortho Tri-Cyclen, Estrostep, Beyaz, and YAZ. [65] [66] [67] Hirsutism is the growth of coarse, dark hair where women typically grow only fine hair or no hair at all. [68] This hair growth on the face, chest, and abdomen is also mediated by higher levels or action of androgens.
Mestranol/norethisterone (Norethin, Noriday, Norinyl, Norquen, Ortho-Novum) Mestranol/noretynodrel (Enavid, Enovid) Quinestrol/etynodiol diacetate (Soluna) Quinestrol/levonorgestrel (Yuèkětíng, Àiyuè) Quinestrol/norgestrel (Compound Norgestrel) Quinestrol/quingestanol acetate (Unovis) For menopausal hormone therapy and/or gynecological ...