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The virus is very common in the general population, infecting 70% to 90% of humans; most people acquire Human polyomavirus 2 in childhood or adolescence. [ 22 ] [ 23 ] [ 24 ] It is found in high concentrations in urban sewage worldwide, leading some researchers to suspect contaminated water as a typical route of infection.
Polyomaviridae is a family of viruses whose natural hosts are primarily mammals and birds. [1] [2] As of 2024, there are eight recognized genera. [3]Fourteen species are known to infect humans, while others, such as Simian Virus 40, have been identified in humans to a lesser extent.
All known human polyomaviruses are fairly common in healthy adult populations and are usually asymptomatic. In studies that profile polyomavirus seroprevalence, or prevalence of detectable antibodies against viral proteins indicating either past or present exposure in immunocompetent adults, estimates of HPyV6 prevalence have ranged from approximately 60–85%, with evidence of low prevalence ...
But wastewater surveillance — the testing of sewage for signs of pathogens such as SARS-CoV-2, poliovirus and mpox virus — has yet to be employed in the tracking of H5N1 bird flu virus.
The first group to publish gave the virus the "Malawi" designation based on the geographic location of the index case, a healthy child from Malawi; the designation "MW polyomavirus" has been included in the International Committee on Taxonomy of Viruses proposed classification of polyomaviruses. It was the 10th human polyomavirus to be ...
Temperature has the highest effect on virus's survival in water since lower temperatures are the key to longer virus survival. For instance, an article published in 2018 noted that it takes one year for certain viruses including poliovirus and echovirus to decrease by a 5log unit at a temperature of 4 ° C, while it takes only a week to obtain ...
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All known human polyomaviruses are fairly common in healthy adult populations and are usually asymptomatic. In studies that profile polyomavirus seroprevalence, or prevalence of detectable antibodies against viral proteins indicating either past or present exposure in immunocompetent adults, HPyV9 tends to have a relatively lower prevalence compared to other human polyomaviruses.