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Belimumab, sold under the brand name Benlysta, is a human monoclonal antibody that inhibits B-cell activating factor (BAFF), [6] also known as B-lymphocyte stimulator (BLyS). [7] It is approved in the United States [8] and Canada, [9] and the European Union [5] to treat systemic lupus erythematosus and lupus nephritis. [10]
This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs that have been withdrawn from market; consequently, the column Use does not necessarily indicate clinical usage. See the list of FDA-approved therapeutic monoclonal antibodies in the monoclonal antibody therapy page.
Belimumab is a monoclonal antibody that inhibits B-cell activating factor and thereby inflammation. It was approved in 2019 by the US Food and Drug Administration to treat the musculoskeletal, cutaneous, and cardiac manifestations of children with cSLE who are over 5 years old. It is given intravenously to cSLE patients with active disease but ...
Biogen and Belgian partner UCB said on Tuesday their experimental lupus treatment met the main goal of a late-stage trial in patients with the chronic disease, a surprise result after the drug ...
Then there’s physical activity: Many of the symptoms of lupus, such as joint pain, fatigue, and depression, may make patients less likely to exercise regularly, Patterson adds, which could ...
Halsey announced in a June 5 Instagram post that she has lupus, an autoimmune disease which was diagnosed in 2022, and a rare white blood-cell disorder. In a prior post announcing the release of ...
RET-mutant medullary thyroid cancer or advanced or metastatic RET fusion-positive thyroid cancer, in radioactive iodine-refractory patients [1] Belimumab: GlaxoSmithKline: active lupus nephritis [1] Osimertinib: AstraZeneca: adjuvant therapy after tumor resection in non-small cell lung cancer with EGFR exon 19 deletions or exon 21 L858R ...
Today, just 13 states offer such coverage. It’s unclear, however, whether the Trump administration will go along with the proposal, which it would have to finalize and implement.