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The exocrine pancreas is one of two compartments that include digestive-acting acinar cells and duct cells.They represent an extension of the intercalated duct into each pancreatic acinus. [1] These cells are commonly known as duct cells, and secrete an aqueous bicarbonate solution under stimulation by the hormone secretin. They also secrete ...
A diagram of the acinar cells in the pancreas, and will deliver enzymes from the acinar cells to the duodenum. [2] Ductal cells comprise about 10% of the pancreas by number and about 4% in volume. Its function is to secrete bicarbonate and mucins and to form the
The pancreas is an organ of the digestive system and endocrine system of vertebrates. In humans, it is located in the abdomen behind the stomach and functions as a gland. The pancreas is a mixed or heterocrine gland, i.e., it has both an endocrine and a digestive exocrine function. [2] 99% of the pancreas is exocrine and 1% is endocrine.
the pancreas [3] the bulbourethral (Cowper's) glands; The thyroid follicles can also be considered of acinar formation but in this case the follicles, being part of an endocrine gland, act as a hormonal deposit rather than to facilitate secretion. Mucous acini usually stain pale, while serous acini usually stain dark.
PaSCs are located within the peri-acinar spaces of the pancreas and extrude long cytoplasmic processes that surround the base of the acinus. [1] PaSCs compose 4% of the total cell mass in the gland [3] Stellate cells derive their name from their star shape and are located in other organs such as the kidney and lungs. [1]
An exocrine pancreas cell is a pancreatic cell that produces enzymes that are secreted into the small intestine. These enzymes help digest food by releasing enzymes as it passes through the gastrointestinal tract. These include acinar cells, which secrete bicarbonate solution and mucin
Merocrine – the cells of the gland excrete their substances by exocytosis into a duct; for example, pancreatic acinar cells, eccrine sweat glands [dubious – discuss], salivary glands, goblet cells, intestinal glands, tear glands, etc. Apocrine – the apical portion of the cytoplasm in the cell membrane, which contains the excretion, buds off.
The pancreas also receives autonomic innervation. The blood flow into pancreas is regulated by sympathetic nerve fibers, while parasympathetic neurons stimulate the activity of acinar and centroacinar cells. Pancreatic secretion is an aqueous solution of bicarbonate originating from the duct cells and enzymes originating from the acinar cells.