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Omeprazole, sold under the brand names Prilosec and Losec, among others, is a medication used in the treatment of gastroesophageal reflux disease (GERD), peptic ulcer disease, and Zollinger–Ellison syndrome. [1] It is also used to prevent upper gastrointestinal bleeding in people who are at high risk. [1]
In general, proton pump inhibitors are well tolerated, and the incidence of short-term adverse effects is relatively low. The range and occurrence of adverse effects are similar for all of the PPIs, though they have been reported more frequently with omeprazole. This may be due to its longer availability and, hence, clinical experience.
Adverse effects of vitamin B2 are mild. A common side effect of taking vitamin B2 is the production of yellow-orange urine. To address this problem, drinking more water may help to reduce the colour intensity of urine. [10]
All sources agree that omeprazole should be taken with water on an empty stomach (i.e., at least 60 minutes after eating). Most sources also say that you should not eat immediately after taking omeprazole, and you should not take it with food (unless a little bit of applesauce is needed to help swallow it, for people who have trouble taking pills).
Pantoprazole, sold under the brand name Protonix, among others, is a medication used for the treatment of stomach ulcers, short-term treatment of erosive esophagitis due to gastroesophageal reflux disease (GERD), maintenance of healing of erosive esophagitis, and pathological hypersecretory conditions including Zollinger–Ellison syndrome.
The relative risks of different types of citrus fruit have not been systematically studied. [1] Affected drugs typically have an auxiliary label saying "Do not take with grapefruit" on the container, and the interaction is elaborated upon in the package insert. [6] People are advised to ask their physician or pharmacist about drug interactions. [6]
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The side effect profile is similar to that of omeprazole and other commonly used PPIs. [26] The most common side effects include headache, nausea, and diarrhea. [2] Rare side effects include rashes, flu-like symptoms, and infections (including by the gastrointestinal pathogen Clostridioides difficile [27]). [26]