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Formally, diagnosis entails the patient having had schizophrenia within the past year, a number of schizophrenic symptoms, and depression being present for two weeks or more. [5] Mild schizophrenic signs may be withdrawing socially, agitation or hostility, and irregular sleep such as in the case of insomnia and hypersomnia .
The interactions of these risk factors are intricate, as numerous and diverse medical insults from conception to adulthood can be involved. [4] Many theories have been proposed including the combination of genetic and environmental factors may lead to deficits in the neural circuits that affect sensory input and cognitive functions. [5]
Schizophrenia affects around 0.3–0.7% of people at some point in their life. [19] [14] In areas of conflict this figure can rise to between 4.0 and 6.5%. [255] It occurs 1.4 times more frequently in males than females and typically appears earlier in men. [87] Worldwide, schizophrenia is the most common psychotic disorder. [56]
Schizophrenia is diagnosed 1.4 times more frequently in males than females, and typically appears earlier in men [7] —the peak ages of onset schizophrenia are 20–28 years for males and 26–32 years for females. [10] Early Onset schizophrenia in childhood, before the age of 13 can sometimes occur.
Schizophrenia is a debilitating and often misunderstood disorder that affects up to 1% of the world's population. [1] Although schizophrenia is a heavily studied disorder, it has remained largely impervious to scientific understanding; epigenetics offers a new avenue for research, understanding, and treatment.
Schizophreniform disorder is a type of mental illness that is characterized by psychosis and closely related to schizophrenia.Both schizophrenia and schizophreniform disorder, as defined by the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR), have the same symptoms and essential features except for two differences: the level of functional impairment and the duration of symptoms.
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