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A small clinical trial of drug dostarlimab, a monoclonal antibody, got rid of rectal cancer in all patients. More about immunotherapy for cancer treatment. 'Unprecedented' study appears to cure 14 ...
Dostarlimab was approved for the treatment of endometrial cancer in both the United States and the European Union in April 2021. [5] [6] [11] [8] [12] Based on the Garnet trial, dostarlimab gained accelerated approval from the US Food and Drug Administration (FDA) in April 2021, [6] and full approval in February 2023. [7]
idiopathic pulmonary fibrosis (IPF), pancreatic cancer Panitumumab [69] Vectibix: mab: human: epidermal growth factor receptor (EGFR) Y: colorectal cancer: Pankomab: mab: humanized: tumor specific glycosylation of MUC1: ovarian cancer Panobacumab [100] mab: human: Pseudomonas aeruginosa: Pseudomonas aeruginosa infection Parsatuzumab [15] mab ...
The concept of blocking PD-1 and PD-L1 for the treatment of cancer was first published in 2001. [6] Pharmaceutical companies began attempting to develop drugs to block these molecules, and the first clinical trial was launched in 2006, evaluating nivolumab.
Drug Manufacturer Indication Adagrasib: In combination with cetuximab for the treatment of adults with KRAS G12C mutated locally advanced or metastatic colorectal cancer who have been previously treated with fluoropyrimidine-, oxaliplatin-, and irinotecan-based chemotherapy [2]
Squamous cell head and neck cancer or EGFR-positive and KRAS wild-type metastatic colorectal cancer. Infusion-related reactions, skin reactions, hypomagnesaemia, hypocalcaemia, hypokalaemia, blood clots, interstitial lung disease and aseptic meningitis. Denosumab: SC: RANKL inhibitor.
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