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Chloroquine (CQ) then becomes protonated (to CQ 2+), as the digestive vacuole is known to be acidic (pH 4.7); chloroquine then cannot leave by diffusion. Chloroquine caps hemozoin molecules to prevent further biocrystallization of heme, thus leading to heme buildup. Chloroquine binds to heme (or FP) to form the FP-chloroquine complex; this ...
Streptococcus canis is a group G beta-hemolytic species of Streptococcus. [1] It was first isolated in dogs, giving the bacterium its name. These bacteria are characteristically different from Streptococcus dysgalactiae, which is a human-specific group G species that has a different phenotypic chemical composition.
Kennel cough is so named because the infection can spread quickly among dogs in the close quarters of a kennel or animal shelter. Viral and bacterial causes of canine cough are spread through airborne droplets produced by sneezing and coughing. These agents also spread through contact with contaminated surfaces.
In dogs it is most commonly caused by mechanical irritation (such as by entropion, ectropion, or trichiasis), allergies, and keratoconjunctivitis sicca. Any bacterial infection is usually secondary. [72] Eye proptosis is a condition resulting in forward displacement and entrapment of the eye from behind by the eyelids. It is a common result of ...
The two major bacterial pathogens are Anaplasma marginale and Anaplasma phagocytophilum. [3] These microorganisms are Gram-negative, [ 4 ] and infect red blood cells . [ 5 ] Once the host is infected with anaplasmosis, the immune system will try to fight off and kill the infected red blood cells, but will also kill healthy red blood cells. [ 2 ]
E. canis is a small, coccus bacterium with a single circular chromosome.Minute in size, E. canis is smaller than the other species in the genus Ehrlichia. [8] [10]The cell walls of this organism lack peptidoglycans and lipopolysaccharides typically present in at least small amounts in most other Gram-negative bacteria, which is believed to contribute to its ability to resist the immune ...
A scanning electron micrograph depicted a number of Gram-negative Bordetella bronchiseptica bacteria. In veterinary medicine, B. bronchiseptica leads to a range of pathologies in different hosts. It is a serious disease of dogs, pigs, and rabbits, and has been seen in cats, horses, and seals. A PCR test for the pathogen exists. [8]
Knee joint of dog. Piece showing knee joint of dog. An untreated hygroma can develop into a large swelling that stresses the surrounding skin and becomes an open wound with the possibility of infection that is much more difficult to treat. In most cases, a hygroma is a single occurrence for an animal, but other individuals will have repeated ...