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Encephalitis lethargica is an atypical form of encephalitis.Also known as "sleeping sickness" or "sleepy sickness" (distinct from tsetse fly–transmitted sleeping sickness), it was first described in 1917 by neurologist Constantin von Economo [2] [3] and pathologist Jean-René Cruchet. [4]
Awakenings is a 1973 non-fiction book by Oliver Sacks.It recounts the life histories of those who had been victims of the 1920s encephalitis lethargica epidemic. [1] Sacks chronicles his efforts in the late 1960s to help these patients at the Beth Abraham Hospital (now Beth Abraham Center for Rehabilitation and Nursing) in the Bronx, New York. [2]
Encephalitis lethargica is a neurological syndrome that causes lethargy, a “mask like” face, excessive blood in the meninges, and other general neurological symptoms. [5] Officially recognized as its own condition in 1917, it is believed to have existed far longer in human history. [ 5 ]
The number of cases of encephalitis has not changed much over time, with about 250,000 cases a year from 2005 to 2015 in the US. Approximately seven per 100,000 people were hospitalized for encephalitis in the US during this time. [34] In 2015, encephalitis was estimated to have affected 4.3 million people and resulted in 150,000 deaths worldwide.
One of the first instances in which an infectious disease was associated with klazomania was the notable pandemic of the encephalitis lethargica from 1916 to 1927. [1] This pandemic also gave rise to observations of other tics that came to be associated with encephalitis lethargica such as complex vocalizations of blocking, echolalia, palilalia ...
In 1969, Dr. Malcolm Sayer is a dedicated and caring physician at a local hospital in the New York City borough of the Bronx.After working extensively with the catatonic patients who survived the 1919–1930 epidemic of encephalitis lethargica, Sayer discovers that certain stimuli will reach beyond the patients' respective catatonic states.
There is speculation that Hitler may have had Encephalitis lethargica when he was a young adult (in addition to the more substantial case for Parkinsonism in his later years). In 1943, author Frederick Cable Oechsner claimed in his book This Is The Enemy that Hitler had a rhinoplasty in Munich sometime after 1933 to correct the shape of his ...
The latter two have appeared in epidemic form in the United States and are characterized by high fever, prolonged coma (which is responsible for the disease being known as a "sleeping sickness"), and convulsions sometimes followed by death. Encephalitis that results as a complication of another systemic infection is known as parainfectious ...