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The Advanced Light Source (ALS) in Berkeley, California, is home to XM-1, a full-field soft X-ray microscope operated by the Center for X-ray Optics and dedicated to various applications in modern nanoscience, such as nanomagnetic materials, environmental and materials sciences and biology. XM-1 uses an X-ray lens to focus X-rays on a CCD, in a ...
Most data visualization in systems biology is done using mathematically generated models. Researchers will diagram all of the protein, gene, or metabolic pathways in a given biological system, then determine the speed of the reactions in that system using mass action kinetics or enzyme kinetics .
X-ray optics is the branch of optics dealing with X-rays, rather than visible light.It deals with focusing and other ways of manipulating the X-ray beams for research techniques such as X-ray diffraction, X-ray crystallography, X-ray fluorescence, small-angle X-ray scattering, X-ray microscopy, X-ray phase-contrast imaging, and X-ray astronomy.
In biology, the biological cost or metabolic price is a measure of the increased energy metabolism that is required to achieve a function. Drug resistance in microbiology, for instance, has a very high metabolic price, [1] especially for antibiotic resistance. [2]
A typical 3D data set is a group of 2D slice images acquired, for example, by a CT, MRI, or MicroCT scanner. These are usually acquired in a regular pattern (e.g., one slice every millimeter) and usually have a regular number of image pixels in a regular pattern.
There are many methods for failure analysis of damages in microelectronic packages, including laser decapsulation, wet etch decapsulation, optical microscopy, SEM microscopy, and X-ray. The problem with most of these methods is the fact that they are destructive. This means it’s possible that the damage itself will be done during preparation.
The X-ray or neutron scattering curve (intensity versus scattering angle) is used to create a low-resolution model of a protein, shown here on the right picture. One can further use the X-ray or neutron scattering data and fit separate domains (X-ray or NMR structures) into the "SAXS envelope".
Multi-wavelength anomalous diffraction (sometimes Multi-wavelength anomalous dispersion; abbreviated MAD) is a technique used in X-ray crystallography that facilitates the determination of the three-dimensional structure of biological macromolecules (e.g. DNA, drug receptors) via solution of the phase problem.