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As ε decreases, the fixed points come together and annihilate one another; As ε increases, the fixed points appear. dx/dt is denoted as v. Nonlinear dynamical systems can be most easily understood with a one-dimensional example system where the change in some quantity x (e.g. protein concentration) abundance depends only on itself:
Symmetry breaking in pitchfork bifurcation as the parameter ε is varied. ε = 0 is the case of symmetric pitchfork bifurcation.. In a dynamical system such as ¨ + (;) + =, which is structurally stable when , if a bifurcation diagram is plotted, treating as the bifurcation parameter, but for different values of , the case = is the symmetric pitchfork bifurcation.
In biology, pairwise interactions have historically been the focus of intense study. With the recent advances in network science , it has become possible to scale up pairwise interactions to include individuals of many species involved in many sets of interactions to understand the structure and function of larger ecological networks . [ 29 ]
The Systems Biology Graphical Notation (SBGN) is a standard graphical representation intended to foster the efficient storage, exchange and reuse of information about signaling pathways, metabolic networks, and gene regulatory networks amongst communities of biochemists, biologists, and theoreticians.
The notion of system (or apparatus) relies upon the concept of vital or organic function: [2] a system is a set of organs with a definite function. This idea was already present in Antiquity (Galen, Aristotle), but the application of the term "system" is more recent.
Biochemistry, or biological chemistry, is the study of chemical processes within and relating to living organisms. [1] A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology, and metabolism. Over the last decades of the 20th century, biochemistry has become successful at ...
In biochemistry, steady state refers to the maintenance of constant internal concentrations of molecules and ions in the cells and organs of living systems. [1] Living organisms remain at a dynamic steady state where their internal composition at both cellular and gross levels are relatively constant, but different from equilibrium concentrations. [1]
Systems biology is the computational and mathematical analysis and modeling of complex biological systems.It is a biology-based interdisciplinary field of study that focuses on complex interactions within biological systems, using a holistic approach (holism instead of the more traditional reductionism) to biological research.