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[1] [3] Severe symptoms include confusion, seizures, and coma; [1] [2] [9] death can ensue. [10] The causes of hyponatremia are typically classified by a person's body fluid status into low volume, normal volume, or high volume. [4] Low volume hyponatremia can occur from diarrhea, vomiting, diuretics, and sweating. [4]
"Very low levels of sodium in the body, extreme sleep deprivation, very low blood sugar or alcohol withdrawal can trigger sporadic seizures," says Shih. Other times, the cause of a seizure is not ...
Hypernatremia (high blood sodium level, above 145 mEq/L) causes thirst, and due to brain cell shrinkage may cause confusion, muscle twitching, or spasms. With severe elevation, seizures and comas may occur. [11] [12] Death can be caused by ingestion of large amounts of salt at a time (about 1 g per kg of body weight). [13]
Systemic infection with high fever is a common cause of seizures, especially in children. [3] [25] These are called febrile seizures and occur in 2–5% of children between the ages of six months and five years. [26] [25] Acute infection of the brain, such as encephalitis or meningitis are also causes of seizures. [3]
The most common presenting symptom is tonic-clonic seizure, found in 80% of patients. [8] Psychogenic polydipsia should be considered a life-threatening condition, since it has been known to cause severe hyponatraemia, leading to cardiac arrest, coma and cerebral oedema. [3]
Unsuppressed ADH causes a physiologically inappropriate increase in solute-free water being reabsorbed by the tubules of the kidney to the venous circulation leading to hypotonic hyponatremia (a low plasma osmolality and low sodium levels). [2] The causes of SIADH are commonly grouped into categories including: central nervous system diseases ...
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