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Plummer–Vinson syndrome (also known as Paterson–Kelly syndrome [1] or Paterson–Brown-Kelly syndrome in the UK [2]) is a rare disease characterized by dysphagia (difficulty swallowing), iron-deficiency anemia, glossitis (inflammation of the tongue), cheilosis (cracking at the corners of the mouth), and esophageal webs (thin membranes in the esophagus that can cause obstruction). [1]
One of the most frequently used techniques is the "three-drop test". [29] In this test, three drops of liquid are presented to the subject. One of the drops is of the taste stimulus, and the other two drops are pure water. [29] Threshold is defined as the concentration at which the patient identifies the taste correctly three times in a row. [29]
Iron deficiency can also cause shortness of breath, and amplify the symptoms of any chronic condition, such as depression. It can also have an affect on your mood, ability to focus and sleep quality .
They are mainly observed in the Plummer–Vinson syndrome, [3] which is associated with chronic iron deficiency anemia. One in 10 patients with Plummer-Vinson syndrome will eventually develop squamous cell carcinoma of the esophagus, [ 4 ] but it is unclear if esophageal webs in and of themselves are a risk factor.
Here are the common causes of a metallic taste in mouth, and how you can get rid of it. Skip to main content. Sign in. Mail. 24/7 Help. For premium support please call: 800-290-4726 more ...
Dysgeusia (usually a bitter or metallic taste) is present in about 60% of people with BMS, a factor which led to the concept of a defect in sensory peripheral neural mechanisms. [12] Changes in the oral environment, such as changes in the composition of saliva, may induce neuropathy or interruption of nerve transduction.
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